Louis the Illinois counties of Bond, Calhoun, Clinton, Jersey, Macoupin, Madison, Monroe, and St. Louis, MO-IL metropolitan statistical area (MSA)-and the focus of this page-includes the City of St.
Louis and their two populations are generally tabulated separately. Louis County is independent of the City of St. Louis is the focus of the largest metro area in Missouri and the Illinois portion known as Metro East is the second largest metropolitan area in that state. The Mississippi River bisects the metro area geographically between Illinois and Missouri however, the Missouri portion is much more populous. The pre-war city core is on the Mississippi Riverfront on the border with Illinois in the geographic center of the metro area. Louis, and its largest employer is St Louis County, Missouri which lies immediately to the west. Its largest principal city is the independent city of St.
Louis is a bi-state metropolitan statistical area in the United States with its core in both Missouri and Illinois.
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